New England Patriots running back TreVeyon Henderson has a high ankle sprain expected to sideline him multiple games, Pro Football Rumors reported on Oct. 17.
The injury does not require surgery, and Henderson may avoid injured reserve, but the Patriots listed him as questionable for Sunday’s game against the New York Jets.
That creates two separate parts to the Patriots injury update: ESPN’s Adam Schefter reported that Henderson is expected to miss multiple games, while the official injury designation leaves open the possibility that he could play this week.
TreVeyon Henderson Has a High Ankle Sprain
Schefter reported that Henderson’s high ankle sprain is expected to keep him out beyond the Jets game. The running back will not need surgery, according to Schefter, and the Patriots could keep him off injured reserve if his recovery progresses without requiring a longer roster designation.
ESPN’s Mike Reiss reported that Henderson practiced on a limited basis during the week. That work was enough for New England to list him as questionable, rather than ruling him out, but it does not change the expectation that the injury could cost him multiple games.
Henderson’s status will be determined before kickoff against the AFC East rival Jets. Until then, the Patriots’ injury report preserves a possibility of playing while the broader injury expectation points toward at least some missed time.
Patriots Have a Potential Henderson Replacement in Lan Larison
If Henderson cannot play, Reiss reported that the Patriots would elevate Lan Larison from the practice squad. That move would give New England another backfield option alongside Rhamondre Stevenson and Corey Kiner.
Larison’s potential elevation is a roster contingency, not an announcement that he will receive a defined share of the workload. The Patriots would first need to make the move if Henderson is unavailable, with Stevenson and Kiner also positioned to factor into the backfield plan.
The timing matters because New England is also getting wide receiver A.J. Brown back from injured reserve in Week 6, according to the reported injury context. Henderson’s absence would still remove one of the offense’s most productive recent rushing options as the Patriots prepare for the Jets.
Henderson’s Production Before the Injury
Henderson established a significant role during his 2025 rookie season. The second-round pick from Ohio State rushed for 911 yards and nine touchdowns on 180 carries, averaging 5.1 yards per attempt while splitting time with Stevenson.
He also contributed as a receiver in 2025, recording 35 catches for 221 yards and one receiving touchdown on 42 targets. That production helps explain why a high ankle sprain could affect more than the Patriots’ rushing rotation.
Henderson’s 2026 numbers have been more modest through four games. He has rushed for 163 yards on 42 attempts, a 3.9-yard average, and has added two receptions for 22 yards.
The running back also missed New England’s Week 1 loss to the Seattle Seahawks with a different ankle injury, according to the reported season context. The Patriots will now have to manage his latest ankle issue while determining whether he can contribute against New York or needs time away from the lineup.
Latest on Harold Landry’s Patriots Return
The Patriots’ other major injury-related roster question involves edge defender Harold Landry. New England placed Landry on reserve/PUP at the end of August after knee problems that began during the 2025 season.
Head coach Mike Vrabel said Friday, according to Andrew Callahan of the Boston Herald, that “the plan would be for him to return at some point.” That statement establishes the team’s intention, but it does not provide a specific return date or indicate when Landry’s 21-day practice window will open.
Readers can track the broader context in this Harold Landry’s health update, while the coach’s outlook is also addressed in Mike Vrabel’s plan for Landry’s return.
New England has received pass-rush production from other players while Landry remains unavailable. Elijah Ponder has 4.5 sacks, rookie Gabe Jacas has 1.5, and free-agent addition Dre’Mont Jones has one sack in 2026.
According to the reported Pro Football Focus context, Jones ranks 10th, Ponder 11th and Jacas 22nd among 106 qualifying edge defenders. The Patriots rank 12th in the NFL in pass-rush win rate, giving the defense a solid statistical foundation even as it awaits clarity on Landry’s eventual return.
For now, Henderson’s situation is the immediate concern: the Patriots have not ruled him out against the Jets, but Schefter’s multiple-game expectation makes the backfield a position to monitor beyond Sunday’s game.
